diff --git a/examples/react/src/App/routes.ts b/examples/react/src/App/routes.ts
index 2f3d55ba..76ab08e4 100644
--- a/examples/react/src/App/routes.ts
+++ b/examples/react/src/App/routes.ts
@@ -21,6 +21,7 @@ import Interaction from '../examples/Interaction';
 import Intersection from '../examples/Intersection';
 import Layouting from '../examples/Layouting';
 import MultiFlows from '../examples/MultiFlows';
+import MultiSetNodes from '../examples/MultiSetNodes';
 import NodeResizer from '../examples/NodeResizer';
 import NodeTypeChange from '../examples/NodeTypeChange';
 import NodeTypesObjectChange from '../examples/NodeTypesObjectChange';
@@ -180,6 +181,11 @@ const routes: IRoute[] = [
     path: 'layouting',
     component: Layouting,
   },
+  {
+    name: 'Multi setNodes',
+    path: 'multi-setnodes',
+    component: MultiSetNodes,
+  },
   {
     name: 'Multi Flows',
     path: 'multiflows',
diff --git a/examples/react/src/examples/MultiSetNodes/index.tsx b/examples/react/src/examples/MultiSetNodes/index.tsx
index f05c2b50..f04e0ddf 100644
--- a/examples/react/src/examples/MultiSetNodes/index.tsx
+++ b/examples/react/src/examples/MultiSetNodes/index.tsx
@@ -14,52 +14,45 @@ import {
   ReactFlowProvider,
 } from '@xyflow/react';
 
-const initNodes: Node[] = [
-  {
-    id: '1',
+import './style.css';
+
+const initNodes: Node[] = [];
+
+for (let i = 0; i < 100; i++) {
+  initNodes.push({
+    id: i.toString(),
     data: {
-      label: 'hallo',
+      label: `node ${i + 1}`,
     },
-    position: { x: 0, y: 0 },
-  },
-  {
-    id: '2',
-    data: {
-      label: 'world',
-    },
-    position: { x: 200, y: 0 },
-  },
-];
+    position: { x: (i % 10) * 60, y: Math.floor(i / 10) * 60 },
+  });
+}
 
 const initEdges: Edge[] = [];
 
 const CustomNodeFlow = () => {
-  const { setNodes } = useReactFlow();
+  const { setNodes, updateNodeData } = useReactFlow();
   const [nodes, , onNodesChange] = useNodesState(initNodes);
   const [edges, setEdges, onEdgesChange] = useEdgesState(initEdges);
 
   const onConnect = useCallback((connection: Connection) => setEdges((eds) => addEdge(connection, eds)), [setEdges]);
 
-  const updateNodes = () => {
-    setNodes((nds) =>
-      nds.map((n) => {
-        if (n.id === '1') {
-          return { ...n, data: { label: 'updated' } };
-        }
+  const multiSetNodes = () => {
+    nodes.forEach((node) =>
+      setNodes((nds) =>
+        nds.map((n) => {
+          if (n.id === node.id) {
+            return { ...n, data: { label: 'node set' } };
+          }
 
-        return n;
-      })
+          return n;
+        })
+      )
     );
+  };
 
-    setNodes((nds) =>
-      nds.map((n) => {
-        if (n.id === '2') {
-          return { ...n, data: { label: 'updated' } };
-        }
-
-        return n;
-      })
-    );
+  const multiUpdateNodes = () => {
+    nodes.forEach((node) => updateNodeData(node.id, { label: 'node update' }));
   };
 
   return (
@@ -74,7 +67,8 @@ const CustomNodeFlow = () => {
       <Controls />
       <Background />
       <Panel>
-        <button onClick={updateNodes}>update nodes</button>
+        <button onClick={multiSetNodes}>set nodes</button>
+        <button onClick={multiUpdateNodes}>update nodes</button>
       </Panel>
     </ReactFlow>
   );
diff --git a/examples/react/src/examples/MultiSetNodes/style.css b/examples/react/src/examples/MultiSetNodes/style.css
new file mode 100644
index 00000000..11f62226
--- /dev/null
+++ b/examples/react/src/examples/MultiSetNodes/style.css
@@ -0,0 +1,3 @@
+.react-flow .react-flow__node {
+  width: 50px;
+}
diff --git a/packages/react/src/hooks/useReactFlow.ts b/packages/react/src/hooks/useReactFlow.ts
index 198599d5..f933664e 100644
--- a/packages/react/src/hooks/useReactFlow.ts
+++ b/packages/react/src/hooks/useReactFlow.ts
@@ -1,4 +1,4 @@
-import { useCallback, useMemo } from 'react';
+import { useCallback, useMemo, useRef } from 'react';
 import { getElementsToRemove, getOverlappingArea, isRectObject, nodeToRect, type Rect } from '@xyflow/system';
 
 import useViewportHelper from './useViewportHelper';
@@ -30,6 +30,10 @@ export function useReactFlow<NodeType extends Node = Node, EdgeType extends Edge
   const viewportHelper = useViewportHelper();
   const store = useStoreApi();
 
+  // this is used to handle multiple syncronous setNodes calls
+  const setNodesData = useRef<Node[]>();
+  const setNodesTimeout = useRef<ReturnType<typeof setTimeout>>();
+
   const getNodes = useCallback<Instance.GetNodes<NodeType>>(() => {
     return store.getState().nodes.map((n) => ({ ...n })) as NodeType[];
   }, []);
@@ -50,16 +54,30 @@ export function useReactFlow<NodeType extends Node = Node, EdgeType extends Edge
 
   const setNodes = useCallback<Instance.SetNodes<NodeType>>((payload) => {
     const { nodes, setNodes, hasDefaultNodes, onNodesChange } = store.getState();
-    const nextNodes = typeof payload === 'function' ? payload(nodes as NodeType[]) : payload;
+    setNodesData.current = setNodesData.current || nodes;
+    const nextNodes = typeof payload === 'function' ? payload(setNodesData.current as NodeType[]) : payload;
+
+    setNodesData.current = nextNodes;
 
     if (hasDefaultNodes) {
       setNodes(nextNodes);
     } else if (onNodesChange) {
-      const changes =
-        nextNodes.length === 0
-          ? nodes.map((node) => ({ type: 'remove', id: node.id } as NodeRemoveChange))
-          : nextNodes.map((node) => ({ item: node, type: 'reset' } as NodeResetChange<NodeType>));
-      onNodesChange(changes);
+      if (setNodesTimeout.current) {
+        clearTimeout(setNodesTimeout.current);
+      }
+
+      // if there are multiple synchronous setNodes calls, we only want to call onNodesChange once
+      // for this, we use a timeout to wait for the last call and store updated nodes in setNodesData
+      // this is not perfect, but should work in most cases
+      setNodesTimeout.current = setTimeout(() => {
+        const changes =
+          nextNodes.length === 0
+            ? nodes.map((node) => ({ type: 'remove', id: node.id } as NodeRemoveChange))
+            : nextNodes.map((node) => ({ item: node, type: 'reset' } as NodeResetChange<NodeType>));
+        onNodesChange(changes);
+
+        setNodesData.current = undefined;
+      }, 0);
     }
   }, []);